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BC Cancer

  • Film & Socials
A BC Cancer researcher holds a single-cell sample vial up to the light on a rooftop, the Vancouver skyline and snow-capped mountains behind him.

Project overview

Objective

BC Cancer works at the leading edge of cancer research, reading tumours at the level of a single cell's DNA. The science is extraordinary and genuinely hard to picture: sequencing the genomes of thousands of individual cancer cells, then using machine learning to understand why some cells survive treatment when others don't. My job was to translate that: to make a general audience feel the significance of work happening at the scale of three billion letters of DNA per cell.

Produced in partnership with Microsoft, the film also had to show how cloud computing removed the bottleneck that had been holding the research back, without tipping into a technology ad. The scientists, and the patients behind the science, had to stay at the centre. And it had to work across audiences and formats: a launch-event feature, a social cut-down, and an executive summary, from one shoot.

Client
BC Cancer
Industry
Cancer Research
Year
2018
Piece
(04/10)

Process& tools.

01

Direction & interviews

  • three subject-matter experts
  • on location
02

Filming

  • Blackmagic Ursa
  • Canon C200
  • Møvi gimbal
  • interview lighting & lav audio
03

Editing & colour

  • Final Cut Pro
  • DaVinci Resolve
04

Motion graphics & titles

  • After Effects
05

Timelapse

  • Canon 5D

In the work.

Screens and stills from the project.

On location.

Shots from the room where it happened.

A cinema camera and boom rig set up to film an interview in the BC Cancer research library, the subject standing by shelves of Science journals.
On set with a Vancouver skyline backdrop: the crew mics up Microsoft’s Raj Cheema at a round table before his interview, snow-capped mountains through the glass.
A rooftop shoot above the Vancouver skyline: a researcher in a white coat holds a sample as the crew films with a softbox key light.
A finished interview frame from the film: Microsoft’s Raj Cheema mid-answer, framed against the Vancouver skyline and mountains through floor-to-ceiling glass.

The solution.

Solution

I led the creative development and directed the shoot on location at BC Cancer in Vancouver, from the research library and lab benches to a rooftop above the city and the mountains. I planned each interview, set the lighting, captured the audio, and shot the B-roll: single-cell samples in gloved hands, fluorescence microscopy at the monitor, the whiteboard math where the new science actually gets worked out.

The story is built around Dr. Sohrab Shah's own metaphor: that sequencing individual cancer cells is like looking down a microscope for the first time, or launching the Hubble Space Telescope and seeing galaxies. That single image carries the whole piece; it turns an abstract leap in genomics into a moment of discovery anyone can feel.

I interviewed the lead scientist (Dr. Sohrab Shah), a research-team developer (Andrew McPherson), and Microsoft's Raj Cheema, then cut the footage into a suite of deliverables for the launch: a two-to-three-minute feature film, a 30-second social cut-down, and an executive summary. Alongside the video I produced the on-location stills and wrote the social campaign that carried the story across channels. The posts below are paired to the cut-down and the picked quotes.

Thefilm.

BC Cancer: Transforming Cancer Research (feature film).
Read transcript

BC Cancer sits at the leading edge of cancer research, sequencing single cancer cells and using high-performance computing, machine learning and artificial intelligence to understand cancer at the most fundamental level of DNA. Dr. Sohrab Shah: What this is giving us is an unprecedented look into a tumour. It's like being able to look down the microscope for the first time, or launching the Hubble Space Telescope and being able to see galaxies for the first time. We can see the genomes of individual cells, and that allows us to really understand the diversity that exists within a cancer, and ultimately to learn the process by which these tumours acquire resistance to treatment. Raj Cheema, Microsoft Canada: We're looking at the transformation of research and how it's done, and quite possibly the application of that research into clinical medicine. Dr. Sohrab Shah: Our project simply would not be possible without the Microsoft partnership. The cloud computing infrastructure, Microsoft Azure's platform, has allowed us to make progress at a rate we wouldn't have been able to otherwise, and it's been an essential component of our research.

The social campaign

One shoot, written for the feed.

Sample social posts I wrote to run alongside the 30-second cut-down and the campaign’s picked quotes, native to each platform and built from the same day on location.

BC Cancer

bccancer.research

Vancouver, BC

Two researchers study a chalkboard covered in single-cell genomics notation.

SINGLE-CELL GENOMICS

Reading cancer, one cell at a time.

1,284 likes

bccancer.research Every breakthrough starts on a chalkboard. BC Cancer’s researchers are mapping the math behind a fundamentally new way to read a tumour, cell by cell, three billion letters of DNA at a time.

#CancerResearch #SingleCellGenomics #PrecisionMedicine #BCCancer

View all 47 comments · 2 HOURS AGO

BC Cancer

bccancer.research

Vancouver, BC

A researcher studies fluorescence microscopy on a monitor, cancer tissue in red and green.

AT SINGLE-CELL RESOLUTION

This is a tumour, up close.

912 likes

bccancer.research Thousands of individual cells, each imaged and sequenced. “The unit of function is the single cell; to understand the whole system, we have to study the cells one at a time.” — Dr. Sohrab Shah

#Genomics #CancerResearch #MachineLearning #BCCancer

View all 31 comments · 1 DAY AGO

BC Cancer

bccancer.research

Vancouver, BC

A researcher holds a single-cell sample vial to the light on a rooftop, Vancouver behind him.

IT STARTS WITH ONE SAMPLE

The Hubble Telescope of cancer research.

2,047 likes

bccancer.research It all begins here, with a single sample. What comes next is what Dr. Sohrab Shah calls “launching the Hubble Space Telescope and seeing galaxies for the first time”: sequencing, machine learning, and a view into a tumour no one has ever had.

#PrecisionMedicine #CancerResearch #CloudForGood #BCCancer

View all 86 comments · 3 DAYS AGO

BC Cancer

bccancer.research

Vancouver, BC

A pathologist examines a sample through a microscope at BC Cancer.

OLD TOOLS, NEW SCIENCE

400 terabytes and counting.

768 likes

bccancer.research Before the cloud, before the code: the microscope. Old tools and new, pointed at one question: why do some cancers stop responding to treatment? With Microsoft Azure, analysis that took weeks now runs overnight.

#CancerResearch #HPC #SingleCell #BCCancer

View all 22 comments · 5 DAYS AGO

Paired video post

The same story, written long for LinkedIn and cut to 30 seconds for the feed. One day on location becomes a feature film, a social cut-down, an executive summary, and a run of posts, each shaped for where it lands.

BC Cancer

BC Cancer

Provincial Health Services Authority · 41,204 followers

Launch campaign ·

+ Follow

What if you could see a tumour the way astronomers first saw galaxies?

At BC Cancer, the research team is sequencing the genomes of individual cancer cells: thousands per tumour, three billion letters of DNA each. The science was never the bottleneck. Compute was.

With Microsoft Azure, analysis that once took weeks now runs overnight, and BC Cancer is publishing one of the largest single-cell cancer datasets in the world, so researchers everywhere can build on it.

We filmed this story on location in Vancouver, from the lab bench to the rooftop. Here’s the 30-second cut.

#CancerResearch #SingleCellGenomics #PrecisionMedicine #CloudComputing

54689 comments · 112 reposts
Behind the strategy

The project brief.

Before a frame is shot, the film is written on paper. This is the working brief for the BC Cancer piece: the thinking that turned a dense research story into a plan.

Client
BC Cancer (Provincial Health Services Authority)
Partner
Microsoft Canada (Azure)
Deliverables
2–3 min feature film · 30s social cut-down · executive summary (EN)
Timeline
Delivered for a mid-June event showcase
Location
Vancouver: research library, labs, rooftop
Interviews
Lead researcher · Research-team developer · Microsoft Canada lead

Overview

BC Cancer works across three workloads: collecting single-cell samples, sequencing them into data, and running high-performance computing with machine learning to understand cancer at the level of DNA. They had optimized the first two but hit a wall on the third, and an on-prem hardware failure had already cost them data they couldn’t afford to lose again. Microsoft Azure removed the compute bottleneck and added elasticity, disaster recovery, and a platform for collaboration, including publishing their single-cell datasets for researchers worldwide.

The idea

Make the invisible visible. Cancer read one cell at a time is abstract, so the film borrows the lead researcher’s own metaphor: sequencing individual cancer cells is like looking down a microscope for the first time, or launching the Hubble Space Telescope and seeing galaxies. Discovery is the throughline; the cloud is what makes the new telescope possible.

Narrative arc

Beginning: the question that has always limited cancer treatment. Why do some cells survive? Middle: a fundamentally new way to see, cell by cell, and the wall the team hit trying to compute it. Turn: the cloud removes the wall; weeks become overnight; the data becomes shareable with the world. End: what this makes possible, from precision medicine to a dataset that accelerates everyone’s research.

Outline: proof-points

  1. The stakes: treatment resistance lives in single cells.
  2. The breakthrough: single-cell sequencing, and the Hubble analogy.
  3. The bottleneck: three billion nucleotides per cell, hundreds of terabytes, outgrowing on-prem compute.
  4. The solution: Azure elasticity, speed, reliability, and disaster recovery.
  5. The multiplier: publishing the dataset for global collaboration.
  6. The meaning: Microsoft’s view of the transformation of research, into clinical medicine.

Practical elements

Narrative
Interview-driven, no scripted voiceover; the scientists and the Microsoft lead carry it, with B-roll and lower-thirds doing the connective work.
Editing style
Measured and cinematic. Let the science breathe, then lift on the discovery beats.
Graphics
Clean lower-thirds, a simple three-workload motion sequence (collect → sequence → analyze), and a closing slate with the BC Cancer + Microsoft lock-up.
Music
Restrained, hopeful, building: wonder over urgency.

Production considerations

Filmed: interviews with the lead researcher, a research-team developer, and Microsoft’s public-sector lead; B-roll of single-cell samples and vials, fluorescence microscopy, pathology at the microscope, and the whiteboard where the math gets worked out. Locations: research library, labs, and a rooftop above Vancouver, using the mountains and skyline as the film’s sense of place. Kit: Blackmagic Ursa, Canon C200, Møvi gimbal, and a Canon 5D for the timelapses; interview lighting and lav audio.

Next project

Microsoft

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